Positions to fill at Ingenuity Systems

The company Ingenuity Systems has bioinformatics related positions that need to be filled. The jobs require that you relocate to the SF Bay Area.

If you are interested in learning more about these positions contact:

Alecksandr Kutchma

Bioinformatics Scientist

Ingenuity Systems Inc.

T 650-381-5040

F 650-381-5190

M 303-725-4996

akutchma@ingenuity.com

www.ingenuity.com

Or visit the link below to view available positions:

http://tbe.taleo.net/NA6/ats/careers/searchResults.jsp?org=INGENUITYSYSTEMS&cws=1

Post-doc Position:  NCBO

The National Center for Biomedical Ontology (NCBO) is one of the seven National Centers for Biomedical Computing supported by the NIH Roadmap. The NCBO is administered at Stanford University, with partners at the Mayo Clinic, the University at Buffalo, the University of Victoria, and UCSF. The Center provides national technological infrastructure to support the creation, dissemination, and management of biomedical information and knowledge in machine-processable form. The laboratory of Dr. Mark Musen, principal investigator of the NCBO, is seeking a highly motivated and independent post-doctoral trainee to conduct research projects at the interface of the life sciences and the Semantic Web. The post-doc will be involved in ongoing collaborative work that concerns archiving, querying, and reasoning about biological data over the Web. The ideal candidate will have a PhD in Biomedical informatics or Computer Science and an excellent publication record. The position requires strong problem-solving skills and the ability to build software tools in Java. Applicants must possess excellent communication skills and be fluent in both spoken and written English. A background in molecular biology or medicine is highly desirable.  Prior experience working with RDF stores, ontologies, or natural-language processing methods is preferred. This exciting work will be guided by multidisciplinary collaborations with top scientists at Stanford and with collaborating projects of the NCBO as well as with Health Care and Life Sciences interest group of the W3C.

Please send a statement of interest and a current CV to:

Mark A. Musen, M.D., Ph.D.
Professor of Medicine (Biomedical Informatics Research) and, by courtesy, of Computer Science Director, Stanford Center for Biomedical Informatics Research Stanford University
251 Campus Drive, X-215
Stanford, CA 94305-5479 USA
Phone: +1 (650) 725-3390
Fax: +1 (650) 725-7944

musen@Stanford.EDU

Bioinformatics Senior Scientist Wanted

Job Description

Company Description

Stemina Biomarker Discovery’s pioneering cell based assays arise from the strategic convergence of two groundbreaking technologies: human embryonic stem cells and metabolomics.  As a result of the research of University of Wisconsin stem cell scientist Dr. Gabriela Cezar, Stemina discovers and validates biomarkers for high throughput diagnostics and drug screening in a human system.  Metabolomics enables the discovery of small molecules that can be used as therapeutic agents or candidate biomarkers of pharmacological efficacy or toxicity. The human embryonic stem cell metabolome provides a source of candidate biomarkers to predict, diagnose or measure the progress of disease or toxic response.  Stemina provides drug screening, drug discovery and diagnostic development services for pharmaceutical and biotechnology companies under service contracts or joint discovery agreements using its proprietary metabolomics platform.  In addition, Stemina uses mass spectrometry based metabolomics to identify biomarkers for cancer diagnostics and personalized medicine.

Job Purpose

To develop novel tools for bioinformatic analysis of metabolomic data generated by mass spectrometry and to analyze and manage the data in useful biomarker profiles for drug screening, diagnostic tools and potential therapeutic targets.  The candidate should have a track record demonstrating the ability to be self-motivated and self-directing, to develop realistic project plans with timelines, and to solve problems using application of scientific theory.

Essential Job Duties and Responsibilities

• Design and implement small molecule and metabolomic analysis.

• Assist in design and execution of scientific experiments in collaboration with analytical chemistry and cell biology staff.

• Lead the construction, population, and maintenance of databases in support of Stemina’s proprietary efforts.
• Evaluate and develop new and advanced bioinformatics tools and software, making them accessible to internal users.
• Perform comparative analyses of mass spectrometer derived metabolomic data.
• Develop integrated metabolomic database including the development and maintenance of bioinformatics tools for metabolomic annotation and analysis.
• Experience in integrating large data sets from multiple analyses into metabolic sense.
• Experience in developing and utilizing data-mining techniques, algorithm development and statistical analysis.
• Work closely with biologists and analytical chemists in updating and utilizing multiple sources of biological data.
• Contribute to the development of visualization tools for complex biological data and novel algorithms to solve bioinformatics problems.
• Write grant applications at the direction of the Chief Scientific Officer in collaboration with other scientific staff.
• Keep and maintain accurate and detailed records of all research and experiments performed.
• Maintain current technical procedures and quality assurance.
• Attend staff and lab meetings.

Qualifications:

To perform this job successfully, an individual must be able to perform each essential duty satisfactorily.  The requirements listed below are representative of the knowledge, skill, and/or ability required.  Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Education and Experience:

Ph.D in molecular biology, biochemistry, bioinformatics, computational biology, molecular biotechnology or related discipline

• 2-3 years of post-doctoral training experience as well as other relevant work experience
• A good knowledge of programming languages such as R, C/C++ or scripting languages Proficiency with C and Perl in Unix environment; prior experience in handling data acquired from Excel, Unix flat files, Oracle and/or MySQL database.
• At least five years of experience in bioinformatics research and development, preferably in metabolomic, genomic and metagenomic analysis.
• Strong background in biochemistry, specifically understanding of the metabolic pathways is required.
• Broad understanding of bioinformatics tools used for metabolomic, genomic and metagenomic analysis (i.e., assembly, binning, gene calling) and gene function prediction.

Knowledge, Skills and Abilities Required:

• Effective interpersonal, verbal and written communication skills, including public-speaking and presentation skills.
• Ability to maintain high level of confidentiality.
• Ability to effectively communicate with all levels of the organization.
• Demonstrated ability to work well independently as well as a part of a diverse team.
• Ability to maintain experimental consistency.
• Demonstrated ability to work well under pressure and manage multiple tasks with constantly changing priorities.
• Demonstrated ability to troubleshoot problems and recommend actions.
• Knowledge of implementation and design of state-of-the-art algorithms for metabolomic, genomic and metagenomic analysis
• Advanced analytical, organizational, and record-keeping skills
• Proficient computer skills: knowledge of multiple platforms and operating systems, including MS Office and research software programs.

Contact:  Elizabeth L.R. Donley at bdonley@stemina.com

Research Assistant Wanted

A Research assistant is needed for a project on the statistical design of mammography trials.  This position requires ten or more hours a week.  The start date is September 1st, 2008 to June 15th, 2009.   Duties include literature rewiew, paper preparation and editing, and grant writing.  Qualified applicants may also be asked to do computer programming and mathematical derivations.  Students interested in Masters or PH.D projects are welcomed.

To apply:  Please send c.v. and writing sample to Deborah.Glueck@uchsc.edu

Master Laboratory Technician Wanted

The Consortium for Comparative Genomics at the University of Colorado School of Medicine has an opening for a master laboratory technician in its high-throughput genomics laboratory. This is a full-time position funded by the Consortium for Comparative Genomics and the UC Cancer Center. The successful candidate will be expected to perform major and minor facets of molecular biology laboratory work required for running and maintaining the Roche-454 FLX ultra-high throughput genome sequencer operated by the Consortium.

Specific Duties:

The duties of the position holder will center around performing all technical laboratory aspects required to run diverse samples on a 454-FLX high-throughput automated genome sequencer housed in the School of Medicine. Specifically, the job involves assessing sample quality and quantity from users, communicating with users and other directors regarding sample diagnosis and project design, carrying out molecular biology laboratory work including PCR, oligo ligation, and other misc. steps within the 454-FLX sample preparation protocol, and maintaining an organized accounting of reagent use and costs. This position requires close interaction with various project directors as well as smooth integration with other laboratory work housed in the UC Cancer Center Core facility. There is also broad future potential, if desired, for the position to expand into intellectual design and implementation of experiments, and also into specific collaborative work with participating scientists.

Requirements: A master’s degree in a relevant field or equivalent experience is preferred (e.g, bachelor’s degree plus three or more years work experience). The candidate must be a highly motivated, self-organizing and independent worker with the ability to also collaborate in a team setting. Computer literacy is required, and additional computer experience with Unix, and/or programming experience is a plus. Any genomics, DNA sequencing, or statistical experience is also a strong plus, but not absolutely required. Deep understanding of molecular biology is preferred.

Salary:  The salary range for this position is between $35,000 and $65,000 per annum, depending on qualifications.

To apply: Please forward a cover letter, CV/Resume and names of three references to Kathy R. Thomas, Administrative Coordinator, Computational BioScience Program, PO Box 6511, Mailstop 8303, Aurora, CO  80045-0511, or email to Kathy.R.Thomas@uchsc.edu

Review of applicants will begin immediately and continue until the position is filled. Multiple openings may be available.

The University of Colorado is committed to diversity and equality in education and employment.

Postdoctoral Researcher Wanted

The Consortium for Comparative Genomics at the University of Colorado School of Medicine has an opening for a postdoctoral researcher in its high-throughput genomics laboratory. This is a full-time position funded by the Consortium for Comparative Genomics and the UC Cancer Center. The successful candidate will be expected to perform major and minor facets of molecular biology laboratory work required for running and maintaining the Roche-454 FLX ultra-high throughput genome sequencer operated by the Consortium, and contribute intellectually to the comparative genomic research conducted through the consortium. The successful candidate will be expected to subdivide time-effort to maintain an independent genomics-based research program in addition to maintaining the effective sequencing throughput. The position is an excellent opportunity for interested persons to become heavily involved with diverse cutting-edge comparative genomics research (medical and otherwise) in a highly collaborative setting.

Specific Duties:

The duties of the position holder will center around performing and managing technical laboratory aspects required to run experiments on a 454-FLX high-throughput automated genome sequencer housed in the School of Medicine, as well as data analysis. Specifically, this will involve assessing sample quality and quantity from users, communicating with users and other directors regarding sample diagnosis and project design, and carrying out molecular biology laboratory work including PCR, oligo ligation, quality control, and other steps within the 454-FLX sample preparation protocol. This position requires close intellectual interaction with various project directors as well as smooth integration with other laboratory work housed in the UC Cancer Center Core facility. There is excellent potential, if desired, for the position to expand into experimental design and grant-writing related to the postdocs own interests, as well as collaborative work with participating scientists. The successful candidate will be expected to maintain an academic research career as part of their efforts with the Consortium.

Requirements: A Ph.D. degree in a relevant field is required, and further research experience is preferred. The candidate must be a highly motivated, self-organizing and independent worker with the ability to also collaborate in a team setting. Computer literacy is required, and additional computer experience with Unix, and/or programming experience is a plus. Any genomics, DNA sequencing, molecular evolution, or statistical experience is also a strong plus. A deep and broad understanding of molecular biology is essential.

Salary:  The salary range for this position is between $35,000 and $65,000 per annum, depending on qualifications.

To apply: Please forward a cover letter, CV/Resume and names of three references to Kathy R. Thomas, Administrative Coordinator, Computational BioScience Program, PO Box 6511, Mailstop 8303, Aurora, CO  80045-0511, or email to Kathy.R.Thomas@uchsc.edu

Review of applicants will begin immediately and continue until the position is filled. Multiple openings may be available.

The University of Colorado is committed to diversity and equality in education and employment.